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In addition, hirudins potent anticoagulant activity may pose a bleeding risk in the treatment of DKD, and the therapeutic window needs to be strictly defined in clinical studies

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Ionescu, M., & Frohman, L

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Petersburg Institute of Bioregulation and Gerontology of the Northwestern Branch of the Russian Academy of Medical Sciences]

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Combining topical GHK-CU with injectable GHK-CU without accounting for total copper load

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None are randomized controlled trials

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