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This was best summed up in a BMJ editorial last year, which noted that diagnosing B12 deficiency can be "challenging" because no "single specific measurement exists to reliably diagnose or refute the presence of B12 deficiency"

This repeated early timing may increase your risk of gastrointestinal side effects like nausea, vomiting, or constipation without providing additional weight loss benefit

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Nat Rev Neurol 14(3):133150 Chen WW, Zhang X, Huang WJ (2016) Role of neuroinflammation in neurodegenerative diseases

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Chalela JA, et al