In clinical trials (e.g., SURMOUNT-1), tirzepatide led to significant weight loss, an average weight loss of 15%20% of body weight over 72 weeks, when combined with diet and exercise
The primary objective of the STEP UP trial was to demonstrate the superiority of semaglutide 7.2 mg to placebo on weight loss
One of the respondents from the T2DXX input described the future of management of diabetes that they hope will be the gold standard, which included teamwork, cross-training and seeking partnerships (i.e., working with emergency departments to move patients with T2DM out of the emergency room and into the Diabetes Management Centre)
During completion of this study, DMR, MAB and MQL have become employed at Novo Nordisk A/S
doi: 10.1073/pnas.1009078107 98 MielenzM
27 Point mutations in the DNA gyrase or topoisomerase IV genes confer fluoroquinolone resistance