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Serious Safety Warnings Both medications carry serious warnings

These factors included major adverse cardiac events, hypoglycemia, gastrointestinal adverse events, episodes of nausea, vomiting, or diarrhea, and changes in glycated hemoglobin (HbA1c), body weight, blood pressure, heart rate, and estimated glomerular filtration rate

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GLP-1RA treatment was associated with a significant reduction in MACE compared with placebo (HR 0.86, 95% CI 0.810.92)

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Researchers at Olio Labs combined Truvetas real-world electronic health record (EHR) data, pre-clinical rodent models, and single-cell RNA sequencing to explore sex-based differences in GLP-1 drug tolerability