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This is consistent with studies showing that HA can improve the performance of nanoparticle-based drug formulations by extending local retention and reducing systemic absorption [1]
[137] Laboratory [edit] The complete laboratory synthesis of B 12 was achieved by Robert Burns Woodward [138] and Albert Eschenmoser in 1972
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The active metabolite of vitamin B12 is required for the methylation of homocysteine in the production of methionine, which is involved in a number of biochemical processes including the monoamine neurotransmitters metabolism
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