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Low-protein plant-based diets and several anti-diabetic medications have been linked to beneficial microbiome effects (Lau et al., 2021)

10.3390/ijms25063108 6 AmigoJ

While this effect typically diminishes as the body adjusts, it provides indirect evidence that the nitric oxide pathways are responding to the peptide

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DOX release was strongly pH dependent and accelerated under acidic tumor conditions, with 60.3% release at pH 5.5 compared to 22.6% at physiological pH (7.4), following a Fickian diffusion mechanism