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All GLP-1 RAs including the dual agent tirzepatide and oral semaglutide demonstrated CV safety

A lower dose that still produces weight loss but allows adequate nutrition may be the right balance

As a result, women have been encouraged to pair their use with effective contraception

Overall, GLP-1 show promise as a new treatment approach for smoking cessation and could be a valuable addition to existing strategies

More serious risks include pancreatitis, gallbladder disease (cholelithiasis, cholecystitis), diabetic retinopathy complications (particularly with rapid improvement in glucose control), and acute kidney injury due to dehydration from gastrointestinal side effects

Not for children