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Araj-Khodaei M, Ayati MH, Azizi Zeinalhajlou A, et al
Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL
Due to their potential to trigger weight loss, focus on these drugs has shifted in application to obesity, with new drug products using these same ingredients gaining FDA approval for such treatment
Although the weight loss mechanism is not well-understood, GLP-1RAs curb hunger, leading to a reduction in food intake
Other drugs in the broader liver-disease pipeline have shown that improvements in liver fat and improvements in fibrosis can actually be separate
Tirzepatide meets these standards, but retatrutide is not quite there yet
