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During the development and maturation of pancreatic cells, key transcription factors include Pancreatic/duodenal homeobox 1 (Pdx1), neurogenin 3 (NEUROG3), and V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MafA) (Zhu et al., 2017)

Other functions of FOXO4 include DNA repair, and mice that lack FOXO4 are subject to a high burden of DNA damage

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The protective effect of ibuprofen-coupled nanocarriers was investigated against cytokine-induced barrier damage by impedance and permeability measurements