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Es interesante resaltar el hecho de que el aumento de la supervivencia de las clulas cardiacas en respuesta a terapias basadas en GLP-1 tiene un impacto significativo en la funcin cardiaca como se demuestra en la mayora de los estudios mencionados, tanto en el contexto de la isquemia-reperfusin como en el de la IC (tabla 2)25,34,40,42,4451
Glucocorticoid-induced hyperglycemia: A neglected problem
Tao H, Fan S, Zhu T, You L, Zheng D, Yan L, et al
Importantly, in mice GBB is the major metabolite produced from L-carnitine gut metabolism, while in humans TMAO appears to be the major metabolite following L-carnitine challenge (Koeth et al., 2014)
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