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Genetic association studies revealed associations of this polymorphism with maternal risk of DS birth either alone (Zampieri et al., 2012b), or in combination with MTR (combined TCN2 776CC/ MTR 2756AG genotype) (Fintelman-Rodrigues et al., 2009) or MTHFR (combined TCN2 776CG/ MTHFR 677TT genotype) (Liao et al., 2014) polymorphisms

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Experts classify GLP-1 receptor agonists into two types: human GLP-1 backbone agents (e.g., Liraglutide, Dulaglutide, Semaglutide) and exendin-4 backbone agents (e.g., exenatide) (23)

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