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We do not know the optimal human dosing, long-term safety profile in humans, or whether animal results translate directly to human outcomes
In the 3-KO and WT groups, male mice aged 1214 weeks were divided into three subgroups including: saline control, AOD9604 administered at a dose of 250 g/kg/day, and hGH administered at a dose of 1 mg/kg/day
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The sub-30-minute half-life documented in preclinical research provides a pharmacokinetic rationale for twice-daily dosing
2020 Pro-angiogenic effects via VEGFR2 activation, explaining wound healing mechanisms
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