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PMID 3295013

This consumes the cells principal methyl donor and removes nicotinamide from the salvage pathway that regenerates NAD+

Benefit 5: Reduced Inflammation Obesity causes chronic low-grade inflammation in fat tissue

The review confirmed that NNMT-mediated NAD+ depletion impairs mitochondrial function, SIRT activity (particularly SIRT1 and SIRT3), redox balance, and energy metabolism, creating conditions relevant to cardiovascular disease research models

Available in 600mg and 1500mg lyophilized vials

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