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Most practitioners recommend starting at 250-300 mcg daily to assess tolerance, then potentially increasing to 400-500 mcg if initial response is suboptimal and no side effects occur
doi:10.1016/j.bcp.2024.116476 Preparation and storage Research-only handling information
Pyo HK, Yoo HG, Won CH, Lee SH, Kang YJ, Eun HC, Cho KH, Kim KH
When your body lacks this vital nutrient, you may experience a range of debilitating symptoms, including persistent fatigue, anemia, neurological challenges, digestive disruptions, mood swings, muscle weakness, vision impairments, glossitis, and even skin pallor or jaundice
As with headache, distinguishing treatment-related fatigue from background symptoms in obese populations with potential sleep disorders presents methodological challenges
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