They touched on it to some extent in this article, but they need to do a lot more research looking at if they are directly affecting the brain or if its the weight loss and reduction in chronic inflammation thats actually helping
The newly synthesized MT can then bind to excess zinc ions in the cell, reducing the free zinc ion concentration and maintaining the zinc balance [139, 140]
The clinical value of patients being on a drug briefly is small, and serial increases and decreases in weight could be associated with lean muscle mass loss
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They respond more aggressively to stress hormones
Supports metabolic function