Biochim Biophys Acta 1985
These medications have become some of the most effective tools for weight management and type 2 diabetes treatment
I am halting Tirzepatide microdosing because it increased my resting heart rate by 3 bpm, lowered my HRV by 7 and decreased my sleep quality by 10% undefined Bryan Johnson (@bryan_johnson) January 30, 2025 After 3 weeks of microdosing Tirzepatide, I decided to stop the intervention, here is why: My resting heart rate (RHR) increased pic.twitter.com/8QnkdF7DzZ Some clinics already offer microdosing using very small doses of GLP-1s for alleged longevity benefits, such as reduced chronic inflammation and enhanced function of mitochondria, known as the "powerhouses of the cell." The benefits of GLP-1 drugs like Ozempic and Mounjaro go beyond blood sugar regulation and weight loss
(The FDA is expediting review of one such drug, survodutide, for liver-disease patients.) Meanwhile, GLP-1-based drugs appear to protect against cardiovascular disease, even independent of weight loss
Also, because of L-theanines potential to affect blood pressure, some doctors may advise patients on blood pressure medications or those with certain conditions to steer clear
It also boosts your energy, helps with pain, and improves sleep