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The approach should be individualized based on pain severity, functional impairment, and underlying etiology once serious pathology has been excluded
While it is generally well-tolerated, there have been some reports of mild side effects, such as redness or swelling at the injection site, headaches, or dizziness
A novel role of circadian transcription factor DBP in hippocampal plasticity
Major randomized controlled trials did not document suicidal ideation as a primary safety signal, though such serious events may be underdetected in structured trials
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