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Moderate rest periods of 60 to 90 seconds between sets have been shown to maximize the acute hormonal response to resistance training

[18] Upon binding to MT1 receptors, melatonin initiates a cascade of intracellular signaling events that ultimately result in decreased neuronal firing and reduced alertness

doi: 10.2174/1570159X14666160219131357 182 SlyepchenkoA.MaesM.KohlerC