Before L-carnitine, S-5-HT was markedly low in both CFS (83 (57) 36 nmol/l), and hypothyroidism (112 (84) 63 nmol/l)
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By six months, they lost an average of 27 pounds, or almost 11% of their body weight
The safest approach is to restart at the lowest dose and titrate up, though this may not be practical for frequent alternating
The switch from a weekly injectable to a daily oral involves different pharmacokinetics, different dosing schedules, and potentially different efficacy profiles
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