The primary outcome was the impact of GLP-1 agonists on weight loss, including BMI, weight, and WC
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The following is a comparison of the incidence rates of gastrointestinal adverse events with semaglutide at different doses from randomized controlled trials: Serious events and warnings: Rare but serious side effects of semaglutide and dulaglutide are: Pancreatitis (inflammation of the pancreas) Changes in vision (worsening diabetic retinopathy) Gallbladder issues (cholecystitis and cholelithiasis) Injection site reactions (redness, inflammation, infection, and scarring) Severe stomachache Suicidal ideation Excessive burping Mood and behaviour changes Hypoglycemia Allergic or hypersensitivity reaction High risk of aspiration (stomach content entering the respiratory tract) during surgical procedures that require anesthesia or sedation GLP-1 medications are contraindicated for patients with a personal or family history of medullary thyroid carcinoma and MEN 2 syndrome (Multiple endocrine neoplasia type 2 syndrome)

If you want a broader look at storage and shelf life, see this guide on whether tirzepatide expires in the fridge
They also help support long-term firmness by maintaining skin integrity at the cellular level
When used according to the appropriate criteria for Mounjaro, it works through hormonal pathways that influence weight management