Across a range of single and multiple tirzepatide doses, broadly comparable values of median T max (global and Japan, T max range of 2448 h
While treatment with the GLP-1 receptor agonist did not impact the average drinks per calendar day or the number of drinking days, it significantly lowered the number of drinks per drinking day as well as weekly alcohol cravings
Similarly, in the combined case-control and cohort study by Wium-Andersen and colleagues, 33 low doses of metformin, DPP-4 inhibitors, GLP-1 analogs, and SGLT2 inhibitors were associated with a lower risk of depression in patients with diabetes compared to non users, with the lowest risk for sodium-glucose transport protein 2 inhibitor users
What's real and what's hype
These longevity treatments operate separately from the GLP-1 weight loss program and have their own subscription structures
doi: 10.1186/s12974-015-0329-1 64 PeknaMSiqinSde PabloYStokowskaATorinsson NaluaiPeknyM