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In trials with secondary endpoints, such as STEP 9 [38], semaglutide also resulted in significant improvements in obesity-related comorbidities, including osteoarthritis-related pain and rates of reversion to normoglycaemia, further underscoring its broad clinical utility
Ultimately, the right choice between Mounjaro and Wegovy depends on your preference for an injection versus a pill, how your body responds, and what fits best with your daily routine
(August 2016)
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Reduced insulin sensitivity, with increases in fasting blood glucose and HbA1c relative to placebo over 12 months in the same controlled trial, a concern for anyone with existing metabolic risk