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This article examines the potential of GLP-1 RAs in MASH treatment, exploring their mechanisms of action, clinical benefits, developmental challenges, and evaluation strategies in preclinical MASH models

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Fortunately, these agents have a relatively wide therapeutic index

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Increasing evidence from clinical and animal studies suggest that hair greying is an independent predictor of serious dermatological pathologies and other conditions [200], such as vitiligo [133], cardiovascular diseases[41], oculocutaneous albinism [197], and osteoporosis[167]

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Its appeal comes from stability and breadth: BPC-157 stays intact in gastric acid, where most growth-factor peptides break down, and animal studies link it to repair across skin, muscle, tendon, ligament, bone, nerve and the gastrointestinal tract

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