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Its 15-amino-acid sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) is stable in acidic and proteolytic environments, which distinguishes it from most endogenous peptides and makes oral administration viable in animal studies
Head-to-head comparison table The numbers are remarkably close
Angiogenesis concern: Because GHK-Cu promotes blood vessel formation, there is a theoretical concern that it could support tumor vascularization in individuals with active cancer
GHK-Cu binds to copper and delivers it directly to cells
Consider combining with appropriate skincare or wound-care protocols as relevant to individual goals
In preclinical models, it has demonstrated pro-angiogenic, cytoprotective, and anti-inflammatory properties 1-3
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