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Full-length human growth hormone binds to growth hormone receptors distributed throughout the body, triggering a cascade of effects including stimulation of IGF-1 production in the liver, alterations in glucose and insulin metabolism, protein synthesis in muscle tissue, bone growth and remodeling, organ enlargement with prolonged use, and fluid retention
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Post-treatment analysis revealed that FGF-21 reduced BACE1 levels in the brain and reversed the inflammatory imbalance between IL-6, TNF- and IL-10, thereby significantly improving the cognitive function of AD models [99]
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