Recent studies have identified specific transport proteins, such as SLC25A39, which facilitate the import of glutathione into mitochondria
The long-term effects of taking glutathione supplements are unknown, and there is concern that high doses of glutathione may cause adverse effects such as liver damage, kidney damage, and even skin cancer
The increased energy matters
The practical takeaway: the right time to start HRT is when your symptoms are affecting your quality of life and your risk profile supports it
Also discard it if the vial was left unrefrigerated after mixing, froze accidentally, or was handled with questionable sterile technique
For example, age and sex have been reported to be associated with differences in ALT activity, as levels tend to be higher in men than women