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Although garlic preparations and organosulfur compounds could inhibit the growth of H

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Concurrently, the vascular system also grapples with managing the byproducts of oxidative stress generated from both the peripheral circulation and metabolic processes within the brain tissue

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To overcome drug resistance and enhance its cytotoxicity, two derivatives of DOX were synthesized incorporating a sulfonamide moiety: 4-mononitrobenzenesulfonyl DOX (MNS-DOX) and 2,4-dinitrobenzenesulfonyl DOX (DNS-DOX) 94

Development for the obesity indication was discontinued in 2007 as a direct result of that Phase IIb outcome