What they did: They took 80 rats (Wistar strain), completely transected their Achilles tendon (the strongest tendon in the body) and divided them into 3 groups: Control , saline BPC-157 by injection , 10 g/kg into the abdominal cavity BPC-157 in drinking water , 10 g/kg orally After 14 days they tested the tensile strength of the healed tendon and performed histology (microscopic examination of the tissue)
The other 2 said about 80% of their symptoms improved
Excessive cytokine activity, including IL-1, IL-6, and TNF-, amplifies these alterations (Hughes et al
Semaglutide is the only GLP analog with a warning about diabetic retinopathy , which occured in 4.0% of patients (versus 2.7% with placebo)
Verified reviewer The physician I was writing with went over and above
If you want more context on the hormone pathway behind this class of medications, this GLP-1 explainer is a useful companion read