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GLP-1s are great, but it looks like people cant stay on them forever, says James Hamilton, Arrowheads chief medical officer

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Specifically, the researchers suggested that the cleavage of caspase-3 and its substrate called Poly ADP-ribose polymerase (PARP) appeared markedly reduced, by ~43% and ~77% respectively, suggesting that the peptide complex may suppress this cascade of programmed cell death