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Because it works deep in the skin, its highly effective but it can also cause dryness or flaking, especially at first
doi: 10.1108/IJPSM-06-2021-0145/FULL/PDF 217 RuiuML
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1113 Two drug classes that significantly reduce major adverse cardiovascular events (MACE) and death, regardless of the presence of T2D, are sodiumglucose co-transporter inhibitors (SGLTis) and glucagon-like peptide-1 (GLP-1) receptor agonists (RAs)
The beauty and wellness press calls it the industrys star peptide
Translation: you're paying out-of-pocket
There are also several studies reporting novel factors associated with DPN risk
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