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[Correlation between an enzyme (glutathione S-transferase-pi) and effects of [PMID: 8678536] Laboratory literature summary: [Correlation between an enzyme (glutathione S-transferase-pi) and effects of chemotherapy (cisplatin + etoposide)]
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As a regulated form of cell death, ferroptosis can activate different downstream pathways and complex molecular effector mechanisms, leading to cell lysis in different forms and resulting in morphological changes and immune responses [10]
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10.1080/15226514.2016.1203287 36 KoushaM.YeganehS.AmirkolaieA
This depletion occurs because acetaminophen metabolism generates a reactive metabolite (NAPQI) that binds glutathione for neutralization and elimination
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