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It highlights that GLP-1 is no longer viewed just as a "gut hormone" but as a systemic regulator of immune and inflammatory responses
It can often be managed with proper care and consultation with a healthcare professional
doi: 10.1038/oncsis.2014.42 85 ChaturvediRAsimMPiazueloMBYanFBarryDPSierraJCet al
Options for managing tolerance include a brief dose reduction for 4 to 8 weeks ("drug holiday" at a lower dose, not complete cessation), lifestyle optimization to maximize the medication effect, evaluation for other contributing factors (thyroid function, cortisol, sleep quality, medication interactions), and consideration of adding a complementary compound to address specific aspects of the plateau
Many researchers agree that GLP-1RA may be potentially beneficial for patients with neurological diseases, regardless of its glucose-modulating effects [6]
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