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These products are not intended for human dosing, injection, or ingestion
Presented for research literature review only Gabery S et al
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Moreover, an open, single-arm, first-in-human trial of PU-H71 in patients with advanced solid tumors showed that the incidence of grade 2 adverse events such as common nausea, headache, and fatigue was extremely low, and only one patient exhibited a grade 3 adverse event (vomiting) that could be related to PU-H71
The active compound reaches target tissues intact
Exogenous melatonin replaces what is missing, but it does nothing to restore the gland itself
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