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1 Its persistent: the thoughts keep coming back rather than passing Its intrusive: it interrupts work, conversations, and concentration Its unwanted: people describe it as distressing rather than pleasurable It carries a mental cost: the constant preoccupation takes up headspace and can lower quality of life Its also common
Semaglutide (Wegovy) and tirzepatide (Mounjaro) are licensed in the UK and supported by NICE guidance for weight management and type 2 diabetes
Patients with certain FTO patterns may benefit from evening injections that suppress overnight snacking urges, while those with different variants might see better daytime appetite control from morning dosing
Factors such as insulin sensitivity, body composition, cardiovascular health, and previous weight loss attempts all influence which medication is likely to be most effective and appropriate
Rani AJ, Mythili SV
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