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Generics do not need to repeat the same clinical trials conducted by the original manufacturer, Novo Nordisk
One of the concerns about GLP-1 agonists is a higher percentage loss of lean body weight or muscle mass than weight management achieved through diet and lifestyle changes
Gopal Grandhige, MD, is direct with patients about this distinction: self-administering unregulated peptides purchased online carries real risks
Human An earlier review on pharmacotherapy for gestational diabetes reported no human data on the safety of GLP-1 agonists during pregnancy and concluded that these drugs cannot be recommended in pregnancy (30)
Some emerging studies are showing that it may be possible for patients to taper off of weight loss drugs or take lower doses and maintain a lower BMI
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