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JCI Insight 5 , e133429 (2020)
In pancreatic beta cells, GLP-1RA promotes the conversion of proinsulin to mature insulin by upregulating the expression of hormone converting enzymes PC1/3 and PC2, while reducing the proinsulin/insulin ratio and enhancing insulin biological activity
The consistency of reports across social media platforms and health information websites suggests this is a genuine side effect experienced by a significant subset of users
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TABLE 3 Summary of methods used to identify GLP-2R expression throughout the gastrointestinal tract
Pregnancy and breastfeeding insufficient data
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