Clinical trial data shows that the large majority of patients continue treatment successfully through the adjustment period
Its the first such drug approved for weight management since 2014 and is to be used in conjunction with a reduced-calorie diet and regular exercise
But then Eli Lilly launched Zepbound, its weight-loss drug, as sales of its diabetes-focused GLP-1, Mounjaro, also rose
Summary SGLT2-i exert more consistent BP-lowering effects than GLP-1RA, largely due to their diuretic-like action
Head-to-head comparison The SURPASS-2 trial compared tirzepatide directly against semaglutide 1.0mg (not the higher 2.4mg weight management dose)
Personalization Matters More Than Ever Everyones metabolic state, cholesterol profile, hormone balance, gut health, and risk factors differ