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In addition to fiber, gentle movement, such as walking, can also encourage natural bowel movements
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The SURMOUNT-4 continuation trial further demonstrated that maintaining tirzepatide long-term preserves weight loss results, while discontinuation leads to significant weight regain
458,459 Impaired BCAA catabolism/oxidation is associated with contractile dysfunction and heart failure development, 433 and these metabolic disturbances are linked not only to cardiac dysfunction but also to cardiac remodeling and insulin resistance in heart failure patients
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The factors driving discontinuation: GI side effects, age 65, lower income, and lack of meaningful weight loss early in treatment
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