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This means insulin is released only when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia compared to some other diabetes medications
Day JW, Ottaway N, Patterson JT et al (2009) A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
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However, as more people stay on them long term, clinicians must be ready to discuss GLP1 longterm safety in an honest, patient-centered way
In a study of type 2 diabetes patients taking anti-diabetic medication, carnitine supplementation reduced blood sugar levels compared with a placebo
The incidence of depression or self-harm was 8.2 vs 11.7 events/1,000 person-years in the DPP-4i-cohort and 18.2 vs 13.6 events/1,000 person-years in the GLP-1 RA cohort for incretin-based therapies vs sulfonylureas, respectively
