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Watch for early warning signs such as: Dark-colored urine Dry mouth Fatigue Muscle cramps Headache Feeling lightheaded or dizzy Reduced performance during work or exercise The best way to stay ahead of dehydration is to drink fluids consistently throughout the day, replace electrolytes during prolonged sweating, take breaks in the shade or air conditioning, and recognize when symptoms require medical attention

First, we leveraged the All of Us Research Program, a large, diverse, dataset with longitudinal electronic health record data, improving the robustness of the findings to real-world clinical populations with diabetes and/or obesity

As the levels of semaglutide drop, the benefits (such as lower blood sugar and reduced appetite) fade gradually

Nature 407 , 249257 (2000)

Side effects may last for weeks after the last dose is taken