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That said, many people start to feel a real difference in their appetite within the first couple of weeks on semaglutide

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GLP-1

The 2024 Endocrine Society guideline on obesity pharmacotherapy recommends "structured GI symptom monitoring during the first 20 weeks of GLP-1 RA therapy, with proactive patient education on when to seek urgent evaluation" [10]

Safety is also important

Both drugs help manage blood sugar levels and support significant weight loss