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Efficacy and Safety of Retatrutide, a GIP, GLP-1, and Glucagon Receptor Agonist, in People with Type 2 Diabetes and Inadequate Glycaemic Control with Diet and Exercise (TRANSCEND-T2D-1): A Double-Blind, Randomised, Phase 3 Trial
Nature Medicine , 18(6), 843-849
It can stimulate sexual arousal, potentially leading to improved erectile function
Engineered to reduce IGFBP binding extends plasma half-life from ~10 min (native) to ~6 hr (LR3)
This plays a role in overall resilience and recovery
As a result, some people should not use Ozempic
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