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Key Facts The Absolute Risk Expansion: The calculated increase in absolute risk is remarkably small, manifesting as approximately 3 to 4 additional cases of ischemic optic neuropathy per 10,000 patients treated with GLP-1 receptor agonists over a standard 18-month therapeutic window

Discontinue use and consult a healthcare provider if symptoms worsen or spread beyond the injection site

PMID 18444899.

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