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Of course he tried eating well and everything, but now with the medications, its better a 100% change, said Wilmer Cardenas of Santa Clara, who said his husband lost about 100 pounds over about two years using GLP-1s covered by Medi-Cal, Californias version of Medicaid

Semaglutide works by mimicking the incretin hormone GLP-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, and slows gastric emptying

Li Y, Luo X, Liao L, Liu W, Ning Q

If you are already experiencing constipation on semaglutide , begin with a moderate dose and increase gradually over two weeks

Harness the clinically proven benefits of the active ingredient in Ozempic* and Wegovy* for significant, sustainable weight loss

The Phase 3 TRIUMPH-4 trial pushed that even further, with participants losing an average of 71.2 pounds at the highest dose