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Escalation of binding therapy with a bile acid sequestrant resulted in substantial recovery over two months

When to seek medical advice: Severe or persistent abdominal pain (especially if radiating to back or shoulder) Persistent vomiting or inability to keep fluids down Yellowing of the skin or eyes (jaundice) Chest pain or persistent palpitations Unexplained changes in blood glucose levels Difficulty adhering to medication or diabetes management plans Concerns about substance use or mental health For urgent concerns, contact NHS 111 for advice

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Participants in the clinical trials lost up to 24% of their body weight in 48 weeks

When B12 is low, red blood cells become oversized and inefficient (megaloblastic anemia), and oxygen delivery to follicles drops

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