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If these data were unavailable, the brand name of the most recent GLP-1 RA prescription fill was used to infer the indication

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The Phe residue that moves between the open and closed conformation is displayed in orange and the residue forming a hydrogen bond with the ligand is displayed in green

HIV-1 proteins, including Tat, Nef, Vpr, protease, and gp120, modulate ROS-generating systems and induce oxidative stress, thereby promoting the expression of viral genes and proinflammatory lymphokines 114,115,116

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