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Try to avoid changing the dose by more than 50-100 mg (due to nonlinear pharmacokinetics, the levels may respond more strongly than you would expect)
[13] It is available as a generic medication and over the counter
However, for some individuals with residual absorption capabilities, high-dose oral supplements can serve as an alternative
Weight-Based Dosing 200 lbs : 300-500 mcg Obese : May require higher doses, supervised Administration Guidelines Injection Method SubQ for best absorption
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Contraindications Given the limited safety data, conservative contraindications would include pregnancy or plans to become pregnant, breastfeeding, age under 18, severe liver or kidney disease, and any condition requiring medications with unknown interaction potential
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