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STEP, Semaglutide Treatment Effect in People with Obesity
A 2025 systematic review and meta-analysis in JAMA Psychiatry found no overall increase in psychiatric side effects, including depression, with GLP-1 medications, but individual responses still vary, which is why we monitor rather than assume
The higher the dose of semaglutide, the more significant the weight loss
Month 2 (weeks 5-8) demands cold foods over hot, BRAT diet during worst days, and aggressive nausea management through strategic meal timing
For women, muscle preservation matters beyond aesthetics
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