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All cited studies are conducted in rodent or in-vitro systems
The author(s) declared that they were an editorial board member of Frontiers, at the time of submission
Relationships between plasma BDNF levels and post-baseline cognitive outcomes Among cancer patients, higher baseline BDNF levels predicted better self-perceived cognitive abilities (PCA: = 0.19, 95% CI 0.03 to 0.34, p = 0.020), and improved attention scores ( = 0.04, 95% CI 0.004 to 0.08, p = 0.029) and memory scores ( = 0.05, 95% CI 0.01 to 0.09, p = 0.018) at 3- and 6-months post-baseline
Its inexpensive, and it isnt a controlled substance
highlighting its potential development as neuroprotective agent
These patients achieved a median PFS of 8.2 months with alpelisib plus fulvestrant or letrozole
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