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symptoms: nausea, vomiting, abdominal pain, confusion, fruity breath) Dehydration and hypotension (risk factors: diuretic use, lowsalt diet, elderly, renal impairment) Lifethreatening allergic reactions (angioedema, anaphylaxis) Hypoglycemia when combined with insulin or sulfonylureas Pancreatitis (severe abdominal pain radiating to back, nausea, vomiting) Fourniers gangrene (necrotizing fasciitis of perineum) Monitoring and precautions Take Farxiga daily
Skin elasticity using a cutometer was measured at baseline, at 4 weeks, and then 4 weeks after discontinuation of the treatment, which showed significant improvement in skin elasticity, even in sun-exposed skin areas, during these time points compared with baseline values [39]
Injectables are expensive, invasive, difficult to maintain long-term, and often provide only transient benefitsleading to poor compliance and incomplete treatment cycles
The problem was that natural human GLP-1 breaks down very quickly in the body